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Local Delivery Is Critical for Monocyte Chemotactic Protein-1 Mediated Site-Specific Murine Aneurysm Healing

BACKGROUND: Local delivery of monocyte chemotactic protein-1 (MCP-1/CCL2) via our drug-eluting coil has been shown to promote intrasaccular aneurysm healing via an inflammatory pathway. OBJECTIVE: In this study, we validate the importance of local MCP-1 in murine aneurysm healing. Whether systemic,...

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Detalles Bibliográficos
Autores principales: Hourani, Siham, Motwani, Kartik, Wajima, Daisuke, Fazal, Hanain, Jones, Chad H., Doré, Sylvain, Hosaka, Koji, Hoh, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868072/
https://www.ncbi.nlm.nih.gov/pubmed/29615957
http://dx.doi.org/10.3389/fneur.2018.00158