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Lead-Induced Atypical Parkinsonism in Rats: Behavioral, Electrophysiological, and Neurochemical Evidence for a Role of Noradrenaline Depletion

Background: Lead neurotoxicity is a major health problem known as a risk factor for neurodegenerative diseases, including the manifestation of parkinsonism-like disorder. While lead is known to preferentially accumulate in basal ganglia, the mechanisms underlying behavioral disorders remain unknown....

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Detalles Bibliográficos
Autores principales: Sabbar, Mariam, Delaville, Claire, De Deurwaerdère, Philippe, Lakhdar-Ghazal, Nouria, Benazzouz, Abdelhamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868125/
https://www.ncbi.nlm.nih.gov/pubmed/29615861
http://dx.doi.org/10.3389/fnins.2018.00173