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Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape
OBJECTIVE: HCV infection is a leading cause of chronic liver disease and a major indication for liver transplantation. Although direct-acting antivirals (DAAs) have much improved the treatment of chronic HCV infection, alternative strategies are needed for patients with treatment failure. As an esse...
Autores principales: | Colpitts, Che C, Tawar, Rajiv G, Mailly, Laurent, Thumann, Christine, Heydmann, Laura, Durand, Sarah C, Xiao, Fei, Robinet, Eric, Pessaux, Patrick, Zeisel, Mirjam B, Baumert, Thomas F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868241/ https://www.ncbi.nlm.nih.gov/pubmed/28360099 http://dx.doi.org/10.1136/gutjnl-2016-312577 |
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