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Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells

cAMP-dependent protein kinase (PKAc) is a pivotal signaling protein in eukaryotic cells. PKAc has two well-characterized regulatory subunit proteins, RI and RII (each having α and β isoforms), which keep the PKAc catalytic subunit in a catalytically inactive state until activation by cAMP. Previous...

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Detalles Bibliográficos
Autores principales:	Haushalter, Kristofer J., Casteel, Darren E., Raffeiner, Andrea, Stefan, Eduard, Patel, Hemal H., Taylor, Susan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868259/ https://www.ncbi.nlm.nih.gov/pubmed/29378851 http://dx.doi.org/10.1074/jbc.M117.809988

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