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MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure

OBJECTIVE: Acute liver failure (ALF) is characterised by overwhelming hepatocyte death and liver inflammation with massive infiltration of myeloid cells in necrotic areas. The mechanisms underlying resolution of acute hepatic inflammation are largely unknown. Here, we aimed to investigate the impact...

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Detalles Bibliográficos
Autores principales: Triantafyllou, Evangelos, Pop, Oltin T, Possamai, Lucia A, Wilhelm, Annika, Liaskou, Evaggelia, Singanayagam, Arjuna, Bernsmeier, Christine, Khamri, Wafa, Petts, Gemma, Dargue, Rebecca, Davies, Scott P, Tickle, Joseph, Yuksel, Muhammed, Patel, Vishal C, Abeles, Robin D, Stamataki, Zania, Curbishley, Stuart M, Ma, Yun, Wilson, Ian D, Coen, Muireann, Woollard, Kevin J, Quaglia, Alberto, Wendon, Julia, Thursz, Mark R, Adams, David H, Weston, Chris J, Antoniades, Charalambos G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868289/
https://www.ncbi.nlm.nih.gov/pubmed/28450389
http://dx.doi.org/10.1136/gutjnl-2016-313615