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Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction

OBJECTIVE: To investigate the beneficial role of prebiotics on endothelial dysfunction, an early key marker of cardiovascular diseases, in an original mouse model linking steatosis and endothelial dysfunction. DESIGN: We examined the contribution of the gut microbiota to vascular dysfunction observe...

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Detalles Bibliográficos
Autores principales: Catry, Emilie, Bindels, Laure B, Tailleux, Anne, Lestavel, Sophie, Neyrinck, Audrey M, Goossens, Jean-François, Lobysheva, Irina, Plovier, Hubert, Essaghir, Ahmed, Demoulin, Jean-Baptiste, Bouzin, Caroline, Pachikian, Barbara D, Cani, Patrice D, Staels, Bart, Dessy, Chantal, Delzenne, Nathalie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868295/
https://www.ncbi.nlm.nih.gov/pubmed/28377388
http://dx.doi.org/10.1136/gutjnl-2016-313316