Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells

BACKGROUND: Previous studies demonstrated that tendon-derived stem cells (TDSCs) were vital healing cells and that mRNA expression of anti-inflammatory cytokine IL-6 was significantly upregulated in injured tendons. The aim of the present study was to investigate the effects of IL-6 on the TDSCs in...

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Detalles Bibliográficos
Autores principales: Chen, Siwei, Deng, Ganming, Li, Kaiqun, Zheng, Haonan, Wang, Gang, Yu, Bin, Zhang, Kairui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868364/
https://www.ncbi.nlm.nih.gov/pubmed/29547593
http://dx.doi.org/10.12659/MSM.908802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868364/
https://www.ncbi.nlm.nih.gov/pubmed/29547593
http://dx.doi.org/10.12659/MSM.908802

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