Cargando…

REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells

REC8 is a component of the meiotic cohesion complex that plays a critical role in chromosome dynamics during meiosis. However, the functional role of REC8 in gastric cancer has not been elucidated. In the present study, REC8 suppressed the growth and metastasis of gastric cancer cells in vitro. Whol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Junhong, Geng, Lanlan, Duan, Gaoyang, Xu, Wanfu, Cheng, Yang, Huang, Zhiliang, Zhou, Zhenwen, Gong, Sitang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868373/ https://www.ncbi.nlm.nih.gov/pubmed/29393474 http://dx.doi.org/10.3892/or.2018.6244

Ejemplares similares

Rabeprazole inhibits inflammatory reaction by inhibition of cell pyroptosis in gastric epithelial cells
por: Xie, Jing, et al.
Publicado: (2021)

PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway
por: Cheng, Yang, et al.
Publicado: (2018)

REC8 suppresses tumor angiogenesis by inhibition of NF-κB-mediated vascular endothelial growth factor expression in gastric cancer cells
por: Liu, Miao, et al.
Publicado: (2020)

Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells
por: Li, Musheng, et al.
Publicado: (2020)

MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis
por: Xu, Wanfu, et al.
Publicado: (2017)

Long Noncoding RNA Expression Signatures of Colon Cancer Based on the ceRNA Network and Their Prognostic Value
por: Cheng, Yang, et al.
Publicado: (2019)

Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease
por: Pan, Wenxu, et al.
Publicado: (2023)

Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages
por: Fu, Ming, et al.
Publicado: (2023)

Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma
por: Cheng, Yang, et al.
Publicado: (2019)

Helicobacter pylori promotes gastric intestinal metaplasia through activation of IRF3-mediated kynurenine pathway
por: Liang, Xinhua, et al.
Publicado: (2023)

REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype
por: Yu, J, et al.
Publicado: (2017)

Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function
por: Zhang, Shunxian, et al.
Publicado: (2019)

Evaluation of Monocarboxylate Transporter 4 in Inflammatory Bowel Disease and Its Potential Use as a Diagnostic Marker
por: He, Liying, et al.
Publicado: (2018)

CD147 Aggravated Inflammatory Bowel Disease by Triggering NF-κB-Mediated Pyroptosis
por: Xu, Zhaohui, et al.
Publicado: (2020)

A new meroterpenoid functions as an anti-tumor agent in hepatoma cells by downregulating mTOR activation and inhibiting EMT
por: Wan, Haoqiang, et al.
Publicado: (2018)

EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway
por: Wang, Yuanyang, et al.
Publicado: (2023)

Chrysin Inhibits TNFα-Induced TSLP Expression through Downregulation of EGR1 Expression in Keratinocytes
por: Yeo, Hyunjin, et al.
Publicado: (2021)

Evaluation of a new fluorescence quantitative PCR test for diagnosing Helicobacter pylori infection in children
por: Ou, Zhiying, et al.
Publicado: (2013)

High glucose alters tendon homeostasis through downregulation of the AMPK/Egr1 pathway
por: Wu, Yu-Fu, et al.
Publicado: (2017)

Gastrulation EMT Is Independent of P-Cadherin Downregulation
por: Moly, Pricila K., et al.
Publicado: (2016)

Downregulation of BLM RecQ helicase inhibits proliferation, promotes the apoptosis and enhances the sensitivity of bladder cancer cells to cisplatin
por: Feng, Sujuan, et al.
Publicado: (2022)

Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC
por: Wang, Wenjuan, et al.
Publicado: (2019)

Egr2 and Egr3 are the unique regulators for systemic autoimmunity
por: Sumitomo, Shuji, et al.
Publicado: (2013)

Bacillus subtilis RecA and its accessory factors, RecF, RecO, RecR and RecX, are required for spore resistance to DNA double-strand break
por: Vlašić, Ignacija, et al.
Publicado: (2014)

Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114
por: Sasanuma, Hiroyuki, et al.
Publicado: (2007)

REC8 inhibits proliferation, migration and invasion of breast cancer cells by targeting CDC20
por: He, Shaodan, et al.
Publicado: (2022)

Raddeanin A inhibited epithelial-mesenchymal transition (EMT) and angiogenesis in glioblastoma by downregulating β-catenin expression
por: Wu, Bingshan, et al.
Publicado: (2021)

Klotho prevents epithelial–mesenchymal transition through Egr-1 downregulation in diabetic kidney disease
por: Li, Yang, et al.
Publicado: (2021)

RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli
por: Henrikus, Sarah S, et al.
Publicado: (2019)

Genetic or siRNA inhibition of MBD2 attenuates the UUO- and I/R-induced renal fibrosis via downregulation of EGR1
por: Ai, Kai, et al.
Publicado: (2022)

Temozolomide protects against the progression of glioblastoma via SOX4 downregulation by inhibiting the LINC00470‐mediated transcription factor EGR2
por: Li, Wenyang, et al.
Publicado: (2023)

REC, Drosophila MCM8, Drives Formation of Meiotic Crossovers
por: Blanton, Hunter L, et al.
Publicado: (2005)

miR-34a induces neutrophil apoptosis by regulating Cdc42-WASP-Arp2/3 pathway-mediated F-actin remodeling and ROS production
por: Cao, Meiwan, et al.
Publicado: (2022)

FOXK2 downregulation suppresses EMT in hepatocellular carcinoma
por: Kong, Jian, et al.
Publicado: (2020)

The RecD2 helicase balances RecA activities
por: Ramos, Cristina, et al.
Publicado: (2022)

Clinical Significance of CD147 in Children with Inflammatory Bowel Disease
por: Wang, Hongli, et al.
Publicado: (2020)

ASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT
por: Zuo, Qingsong, et al.
Publicado: (2018)

Expression and prognostic value of the transcription factors EGR1 and EGR3 in gliomas
por: Knudsen, Arnon Møldrup, et al.
Publicado: (2020)

Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE(2) Synthesis of HBx(+) Hepatocytes
por: Ma, Yan, et al.
Publicado: (2015)

Construction of recB-recD genetic fusion and functional analysis of RecBDC fusion enzyme in Escherichia coli
por: Portakal, Oytun, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_jadd1pqfv4o2mank43f1ojgmea