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The price of flexibility – a case study on septanoses as pyranose mimetics

Seven-membered ring mimetics of mannose were studied as ligands for the mannose-specific bacterial lectin FimH, which plays an essential role in the first step of urinary tract infections (UTI). A competitive binding assay and isothermal titration calorimetry (ITC) experiments indicated an approxima...

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Detalles Bibliográficos
Autores principales:	Sager, Christoph P., Fiege, Brigitte, Zihlmann, Pascal, Vannam, Raghu, Rabbani, Said, Jakob, Roman P., Preston, Roland C., Zalewski, Adam, Maier, Timm, Peczuh, Mark W., Ernst, Beat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868388/ https://www.ncbi.nlm.nih.gov/pubmed/29629131 http://dx.doi.org/10.1039/c7sc04289b

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