Short hairpin RNA-mediated gene silencing of ADAM17 inhibits the growth of breast cancer MCF-7 cells in vitro and in vivo and its mechanism of action

A disintegrin and metalloprotease 17 (ADAM17) is highly expressed in many malignant tumors and is closely related to their development. We showed in a previous study that silencing of ADAM17 by siRNA inhibited the growth of MCF-7 breast cancer cells in vitro and in vivo. In the present study, we inv...

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Detalles Bibliográficos
Autores principales: Hu, Baoshan, Meng, Xiangchao, Zhang, Yan, Hossain, Mohammad Monir, Wu, Lijun, Zhang, Yuanyuan, Peng, Xiaobing, Zhang, Xuepeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868399/
https://www.ncbi.nlm.nih.gov/pubmed/29393483
http://dx.doi.org/10.3892/or.2018.6237

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