Cargando…

Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy

Gastric cancer is the fifth most common cancer worldwide and Hippo-Yap is the novel signaling pathway which plays an important role in gastric cancer tumor development and progression. However, little insight is available to date regarding the specific role of Yes-associated protein (Yap) in gastric...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Hongzhu, Qiu, Chengmin, Sun, Weiwei, Gu, Minmin, Xiao, Feng, Zou, Jue, Zhang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868403/ https://www.ncbi.nlm.nih.gov/pubmed/29436693 http://dx.doi.org/10.3892/or.2018.6252

Ejemplares similares

NR4A1-induced increase in the sensitivity of a human gastric cancer line to TNFα-mediated apoptosis is associated with the inhibition of JNK/Parkin-dependent mitophagy
por: Yan, Hongzhu, et al.
Publicado: (2017)

Mammalian STE20-like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2-mediated mitophagy
por: Hu, Yongli, et al.
Publicado: (2020)

Anti-Tumor Effects of Mfn2 in Gastric Cancer
por: Zhang, Ge-Er, et al.
Publicado: (2013)

Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy
por: Benischke, Anne-Sophie, et al.
Publicado: (2017)

YAP promotes gastric cancer cell survival and migration/invasion via the ERK/endoplasmic reticulum stress pathway
por: Liu, Haibin, et al.
Publicado: (2019)

Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy
por: Yang, Lixuan, et al.
Publicado: (2023)

MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice
por: Miao, Junru, et al.
Publicado: (2021)

CircHIPK3 relieves vascular calcification via mediating SIRT1/PGC-1α/MFN2 pathway by interacting with FUS
por: Feng, Siyi, et al.
Publicado: (2023)

The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes
por: Huo, Yinbo, et al.
Publicado: (2022)

Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway
por: Li, Hai-Jun, et al.
Publicado: (2017)

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
por: McLelland, Gian-Luca, et al.
Publicado: (2018)

VCP/p97 cofactor UBXN1/SAKS1 regulates mitophagy by modulating MFN2 removal from mitochondria
por: Mengus, Chantal, et al.
Publicado: (2021)

Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis
por: Yang, Xiaofan, et al.
Publicado: (2020)

PINK1‐Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B‐Mediated Hippo‐YAP/TAZ Pathway
por: Fan, Shengjun, et al.
Publicado: (2020)

SIRT5 regulation of ammonia-induced autophagy and mitophagy
por: Polletta, Lucia, et al.
Publicado: (2015)

Betaine enhances the cellular survival via mitochondrial fusion and fission factors, MFN2 and DRP1
por: Jung Kim, Min
Publicado: (2018)

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
por: Chen, Hsiuchen, et al.
Publicado: (2003)

Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction
por: Hall, A R, et al.
Publicado: (2016)

MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation
por: Chen, Wei, et al.
Publicado: (2020)

Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2
por: Sloat, S. R., et al.
Publicado: (2019)

miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2
por: Zhang, Hao, et al.
Publicado: (2022)

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion
por: Georgiadou, Eleni, et al.
Publicado: (2022)

Correction: Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction
por: Hall, A. R., et al.
Publicado: (2021)

Resveratrol Reestablishes Mitochondrial Quality Control in Myocardial Ischemia/Reperfusion Injury through Sirt1/Sirt3-Mfn2-Parkin-PGC-1α Pathway
por: Zheng, Minsi, et al.
Publicado: (2022)

Mfn2 Affects Embryo Development via Mitochondrial Dysfunction and Apoptosis
por: Zhao, Na, et al.
Publicado: (2015)

Mitochondrial Dynamics Related Genes -MFN1, MFN2 and DRP1 Polymorphisms are Associated with Risk of Lung Cancer
por: Liang, Xiaohua, et al.
Publicado: (2021)

Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia–Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 Signaling
por: Liu, Min, et al.
Publicado: (2020)

Vanillic acid attenuates H(2)O(2)-induced injury in H9c2 cells by regulating mitophagy via the PINK1/Parkin/Mfn2 signaling pathway
por: Mei, Manxue, et al.
Publicado: (2022)

Melatonin attenuates spatial learning and memory dysfunction in developing rats by suppressing isoflurane-induced endoplasmic reticulum stress via the SIRT1/Mfn2/PERK signaling pathway
por: Fang, Xi, et al.
Publicado: (2022)

Retraction: Mfn2 overexpression attenuates Cardio-Cerebrovascular Ischemia–Reperfusion injury through mitochondrial fusion and activation of the AMPK/Sirt3 signaling
Publicado: (2022)

YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo
por: Sun, Dan, et al.
Publicado: (2016)

SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
por: Lang, Alexander, et al.
Publicado: (2017)

Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway
por: Qiao, Huiying, et al.
Publicado: (2018)

Berberine suppressed sarcopenia insulin resistance through SIRT1-mediated mitophagy
por: Su, Xiaojuan, et al.
Publicado: (2023)

Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations
por: Detmer, Scott A., et al.
Publicado: (2007)

Laminar flow inhibits the Hippo/YAP pathway via autophagy and SIRT1-mediated deacetylation against atherosclerosis
por: Yuan, Ping, et al.
Publicado: (2020)

Elaiophylin Inhibits Tumorigenesis of Human Lung Adenocarcinoma by Inhibiting Mitophagy via Suppression of SIRT1/Nrf2 Signaling
por: Ji, Jiali, et al.
Publicado: (2022)

SIRT2-KLF4 Interactions are Critical for Myeloma Survival and Migration
por: Lu, Chunjuan, et al.
Publicado: (2022)

Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo
por: Zhao, Fanpeng, et al.
Publicado: (2021)

MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival
por: Park, Y-Y, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lhh91rlcqc3f5uv4h8pmfcqtdc