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Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

Due to their remarkable parasitocidal activity, artemisinins represent the key components of first-line therapies against Plasmodium falciparum malaria. However, the decline in efficacy of artemisinin-based drugs jeopardizes global efforts to control and ultimately eradicate the disease. To better u...

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Detalles Bibliográficos
Autores principales: Rocamora, Frances, Zhu, Lei, Liong, Kek Yee, Dondorp, Arjen, Miotto, Olivo, Mok, Sachel, Bozdech, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868857/
https://www.ncbi.nlm.nih.gov/pubmed/29538461
http://dx.doi.org/10.1371/journal.ppat.1006930

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