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Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts

Glycans are inherently heterogeneous, yet glycosylation is essential in eukaryotes, and glycans show characteristic cell type-dependent distributions. By using an immortalized human mesenchymal stromal cell (MSC) line model, we show that both N- and O-glycan processing in the Golgi functionally modu...

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Detalles Bibliográficos
Autores principales: Wilson, Katherine M., Jagger, Alistair M., Walker, Matthew, Seinkmane, Estere, Fox, James M., Kröger, Roland, Genever, Paul, Ungar, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868951/
https://www.ncbi.nlm.nih.gov/pubmed/29361539
http://dx.doi.org/10.1242/jcs.209452

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