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Codon usage biases co-evolve with transcription termination machinery to suppress premature cleavage and polyadenylation
Codon usage biases are found in all genomes and influence protein expression levels. The codon usage effect on protein expression was thought to be mainly due to its impact on translation. Here, we show that transcription termination is an important driving force for codon usage bias in eukaryotes....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869017/ https://www.ncbi.nlm.nih.gov/pubmed/29547124 http://dx.doi.org/10.7554/eLife.33569 |