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An “Old” protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses

Here we review the evolving story of the coronavirus endoribonuclease (EndoU). Coronavirus EndoU is encoded within the sequence of nonstructural protein (nsp) 15, which was initially identified as a component of the viral replication complex. Biochemical and structural studies revealed the enzymatic...

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Detalles Bibliográficos
Autores principales: Deng, Xufang, Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869138/
https://www.ncbi.nlm.nih.gov/pubmed/29307596
http://dx.doi.org/10.1016/j.virol.2017.12.024

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