Cargando…
An “Old” protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses
Here we review the evolving story of the coronavirus endoribonuclease (EndoU). Coronavirus EndoU is encoded within the sequence of nonstructural protein (nsp) 15, which was initially identified as a component of the viral replication complex. Biochemical and structural studies revealed the enzymatic...
Autores principales: | Deng, Xufang, Baker, Susan C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869138/ https://www.ncbi.nlm.nih.gov/pubmed/29307596 http://dx.doi.org/10.1016/j.virol.2017.12.024 |
Ejemplares similares
-
Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors
por: Hackbart, Matthew, et al.
Publicado: (2020) -
Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages
por: Volk, Aaron, et al.
Publicado: (2020) -
MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells
por: Comar, Courtney E., et al.
Publicado: (2022) -
Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses
por: Deng, Xufang, et al.
Publicado: (2019) -
Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3
por: Wu, Yang, et al.
Publicado: (2023)