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Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages

Despite the rapidly expanding use of antibody‐based therapeutics to treat cancer, knowledge of the cellular processes following phagocytosis of antibody‐opsonized tumor cells is limited. Here we report the formation of a phagosome‐associated vacuole that is observed in macrophages as these degradati...

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Detalles Bibliográficos
Autores principales: Velmurugan, Ramraj, Ramakrishnan, Sreevidhya, Kim, Mingin, Ober, Raimund J., Ward, E. Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869154/
https://www.ncbi.nlm.nih.gov/pubmed/29437282
http://dx.doi.org/10.1111/tra.12552