Peripheral CB1 Receptor Neutral Antagonist, AM6545, Ameliorates Hypometabolic Obesity and Improves Adipokine Secretion in Monosodium Glutamate Induced Obese Mice

Effect of peripheral cannabinoid receptor 1 (CB1R) blockade by AM6545 in the monosodium glutamate (MSG)-induced hypometabolic and hypothalamic obesity was observed, and the impact on intraperitoneal adipose tissue and adipokines was investigated. The MSG mice is characterized by excessive abdominal...

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Detalles Bibliográficos
Autores principales: Ma, Haiming, Zhang, Guina, Mou, Chunrong, Fu, Xiujuan, Chen, Yadan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869198/
https://www.ncbi.nlm.nih.gov/pubmed/29615900
http://dx.doi.org/10.3389/fphar.2018.00156

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