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Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer

INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, the...

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Autores principales: Safdari, Reza, Arpanahi, Hadi Kazemi, Langarizadeh, Mostafa, Ghazisaiedi, Marjan, Dargahi, Hossein, Zendehdel, Kazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869226/
https://www.ncbi.nlm.nih.gov/pubmed/29719308
http://dx.doi.org/10.5455/aim.2018.26.19-23
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author Safdari, Reza
Arpanahi, Hadi Kazemi
Langarizadeh, Mostafa
Ghazisaiedi, Marjan
Dargahi, Hossein
Zendehdel, Kazem
author_facet Safdari, Reza
Arpanahi, Hadi Kazemi
Langarizadeh, Mostafa
Ghazisaiedi, Marjan
Dargahi, Hossein
Zendehdel, Kazem
author_sort Safdari, Reza
collection PubMed
description INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, there is no systematic approach for early diagnosis of gastric cancer. OBJECTIVE: to develop a fuzzy expert system that can identify gastric cancer risk levels in individuals. METHODS: This system was implemented in MATLAB software, Mamdani inference technique applied to simulate reasoning of experts in the field, a total of 67 fuzzy rules extracted as a rule-base based on medical expert’s opinion. RESULTS: 50 case scenarios were used to evaluate the system, the information of case reports is given to the system to find risk level of each case report then obtained results were compared with expert’s diagnosis. Results revealed that sensitivity was 92.1% and the specificity was 83.1%. CONCLUSIONS: The results show that is possible to develop a system that can identify High risk individuals for gastric cancer. The system can lead to earlier diagnosis, this may facilitate early treatment and reduce gastric cancer mortality rate.
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spelling pubmed-58692262018-05-01 Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer Safdari, Reza Arpanahi, Hadi Kazemi Langarizadeh, Mostafa Ghazisaiedi, Marjan Dargahi, Hossein Zendehdel, Kazem Acta Inform Med Original Paper INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, there is no systematic approach for early diagnosis of gastric cancer. OBJECTIVE: to develop a fuzzy expert system that can identify gastric cancer risk levels in individuals. METHODS: This system was implemented in MATLAB software, Mamdani inference technique applied to simulate reasoning of experts in the field, a total of 67 fuzzy rules extracted as a rule-base based on medical expert’s opinion. RESULTS: 50 case scenarios were used to evaluate the system, the information of case reports is given to the system to find risk level of each case report then obtained results were compared with expert’s diagnosis. Results revealed that sensitivity was 92.1% and the specificity was 83.1%. CONCLUSIONS: The results show that is possible to develop a system that can identify High risk individuals for gastric cancer. The system can lead to earlier diagnosis, this may facilitate early treatment and reduce gastric cancer mortality rate. Academy of Medical sciences 2018 /pmc/articles/PMC5869226/ /pubmed/29719308 http://dx.doi.org/10.5455/aim.2018.26.19-23 Text en © 2018 Reza Safdari, Hadi Kazemi Arpanahi, Mostafa Langarizadeh, Marjan Ghazisaiedi, Hossein Dargahi, Kazem Zendehdel http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Safdari, Reza
Arpanahi, Hadi Kazemi
Langarizadeh, Mostafa
Ghazisaiedi, Marjan
Dargahi, Hossein
Zendehdel, Kazem
Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title_full Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title_fullStr Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title_full_unstemmed Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title_short Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
title_sort design a fuzzy rule-based expert system to aid earlier diagnosis of gastric cancer
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869226/
https://www.ncbi.nlm.nih.gov/pubmed/29719308
http://dx.doi.org/10.5455/aim.2018.26.19-23
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