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Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer
INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academy of Medical sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869226/ https://www.ncbi.nlm.nih.gov/pubmed/29719308 http://dx.doi.org/10.5455/aim.2018.26.19-23 |
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author | Safdari, Reza Arpanahi, Hadi Kazemi Langarizadeh, Mostafa Ghazisaiedi, Marjan Dargahi, Hossein Zendehdel, Kazem |
author_facet | Safdari, Reza Arpanahi, Hadi Kazemi Langarizadeh, Mostafa Ghazisaiedi, Marjan Dargahi, Hossein Zendehdel, Kazem |
author_sort | Safdari, Reza |
collection | PubMed |
description | INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, there is no systematic approach for early diagnosis of gastric cancer. OBJECTIVE: to develop a fuzzy expert system that can identify gastric cancer risk levels in individuals. METHODS: This system was implemented in MATLAB software, Mamdani inference technique applied to simulate reasoning of experts in the field, a total of 67 fuzzy rules extracted as a rule-base based on medical expert’s opinion. RESULTS: 50 case scenarios were used to evaluate the system, the information of case reports is given to the system to find risk level of each case report then obtained results were compared with expert’s diagnosis. Results revealed that sensitivity was 92.1% and the specificity was 83.1%. CONCLUSIONS: The results show that is possible to develop a system that can identify High risk individuals for gastric cancer. The system can lead to earlier diagnosis, this may facilitate early treatment and reduce gastric cancer mortality rate. |
format | Online Article Text |
id | pubmed-5869226 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Academy of Medical sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-58692262018-05-01 Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer Safdari, Reza Arpanahi, Hadi Kazemi Langarizadeh, Mostafa Ghazisaiedi, Marjan Dargahi, Hossein Zendehdel, Kazem Acta Inform Med Original Paper INTRODUCTION: Screening and health check-up programs are most important sanitary priorities, that should be undertaken to control dangerous diseases such as gastric cancer that affected by different factors. More than 50% of gastric cancer diagnoses are made during the advanced stage. Currently, there is no systematic approach for early diagnosis of gastric cancer. OBJECTIVE: to develop a fuzzy expert system that can identify gastric cancer risk levels in individuals. METHODS: This system was implemented in MATLAB software, Mamdani inference technique applied to simulate reasoning of experts in the field, a total of 67 fuzzy rules extracted as a rule-base based on medical expert’s opinion. RESULTS: 50 case scenarios were used to evaluate the system, the information of case reports is given to the system to find risk level of each case report then obtained results were compared with expert’s diagnosis. Results revealed that sensitivity was 92.1% and the specificity was 83.1%. CONCLUSIONS: The results show that is possible to develop a system that can identify High risk individuals for gastric cancer. The system can lead to earlier diagnosis, this may facilitate early treatment and reduce gastric cancer mortality rate. Academy of Medical sciences 2018 /pmc/articles/PMC5869226/ /pubmed/29719308 http://dx.doi.org/10.5455/aim.2018.26.19-23 Text en © 2018 Reza Safdari, Hadi Kazemi Arpanahi, Mostafa Langarizadeh, Marjan Ghazisaiedi, Hossein Dargahi, Kazem Zendehdel http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Paper Safdari, Reza Arpanahi, Hadi Kazemi Langarizadeh, Mostafa Ghazisaiedi, Marjan Dargahi, Hossein Zendehdel, Kazem Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title | Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title_full | Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title_fullStr | Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title_full_unstemmed | Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title_short | Design a Fuzzy Rule-based Expert System to Aid Earlier Diagnosis of Gastric Cancer |
title_sort | design a fuzzy rule-based expert system to aid earlier diagnosis of gastric cancer |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869226/ https://www.ncbi.nlm.nih.gov/pubmed/29719308 http://dx.doi.org/10.5455/aim.2018.26.19-23 |
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