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Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape
A cross‐industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of preclinical QSP modeling in addition to future oppor...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869550/ https://www.ncbi.nlm.nih.gov/pubmed/29349875 http://dx.doi.org/10.1002/psp4.12282 |
| _version_ | 1783309305140740096 |
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| author | Nijsen, Marjoleen J.M.A. Wu, Fan Bansal, Loveleena Bradshaw‐Pierce, Erica Chan, Jason R. Liederer, Bianca M. Mettetal, Jerome T. Schroeder, Patricia Schuck, Edgar Tsai, Alice Xu, Christine Chimalakonda, Anjaneya Le, Kha Penney, Mark Topp, Brian Yamada, Akihiro Spilker, Mary E. |
| author_facet | Nijsen, Marjoleen J.M.A. Wu, Fan Bansal, Loveleena Bradshaw‐Pierce, Erica Chan, Jason R. Liederer, Bianca M. Mettetal, Jerome T. Schroeder, Patricia Schuck, Edgar Tsai, Alice Xu, Christine Chimalakonda, Anjaneya Le, Kha Penney, Mark Topp, Brian Yamada, Akihiro Spilker, Mary E. |
| author_sort | Nijsen, Marjoleen J.M.A. |
| collection | PubMed |
| description | A cross‐industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of preclinical QSP modeling in addition to future opportunities. Our results call attention to the need for an aligned definition and consistent terminology around QSP, yet highlight the broad applicability and benefits preclinical QSP modeling is currently delivering. |
| format | Online Article Text |
| id | pubmed-5869550 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-58695502018-03-28 Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape Nijsen, Marjoleen J.M.A. Wu, Fan Bansal, Loveleena Bradshaw‐Pierce, Erica Chan, Jason R. Liederer, Bianca M. Mettetal, Jerome T. Schroeder, Patricia Schuck, Edgar Tsai, Alice Xu, Christine Chimalakonda, Anjaneya Le, Kha Penney, Mark Topp, Brian Yamada, Akihiro Spilker, Mary E. CPT Pharmacometrics Syst Pharmacol Review A cross‐industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of preclinical QSP modeling in addition to future opportunities. Our results call attention to the need for an aligned definition and consistent terminology around QSP, yet highlight the broad applicability and benefits preclinical QSP modeling is currently delivering. John Wiley and Sons Inc. 2018-02-01 2018-03 /pmc/articles/PMC5869550/ /pubmed/29349875 http://dx.doi.org/10.1002/psp4.12282 Text en © 2018 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Review Nijsen, Marjoleen J.M.A. Wu, Fan Bansal, Loveleena Bradshaw‐Pierce, Erica Chan, Jason R. Liederer, Bianca M. Mettetal, Jerome T. Schroeder, Patricia Schuck, Edgar Tsai, Alice Xu, Christine Chimalakonda, Anjaneya Le, Kha Penney, Mark Topp, Brian Yamada, Akihiro Spilker, Mary E. Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title | Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title_full | Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title_fullStr | Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title_full_unstemmed | Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title_short | Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape |
| title_sort | preclinical qsp modeling in the pharmaceutical industry: an iq consortium survey examining the current landscape |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869550/ https://www.ncbi.nlm.nih.gov/pubmed/29349875 http://dx.doi.org/10.1002/psp4.12282 |
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