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Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva

A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management of blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated polycaprolactone@polypyrrole fibers modified indium-tin oxide (denoted as CuO/PCL@PPy/ITO) electrode...

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Detalles Bibliográficos
Autores principales: Xu, Ting, Jin, Wen, Wang, Zhenzhen, Cheng, Haiyan, Huang, Xinhua, Guo, Xiaoyu, Ying, Ye, Wu, Yiping, Wang, Feng, Wen, Ying, Yang, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869624/
https://www.ncbi.nlm.nih.gov/pubmed/29495508
http://dx.doi.org/10.3390/nano8030133
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author Xu, Ting
Jin, Wen
Wang, Zhenzhen
Cheng, Haiyan
Huang, Xinhua
Guo, Xiaoyu
Ying, Ye
Wu, Yiping
Wang, Feng
Wen, Ying
Yang, Haifeng
author_facet Xu, Ting
Jin, Wen
Wang, Zhenzhen
Cheng, Haiyan
Huang, Xinhua
Guo, Xiaoyu
Ying, Ye
Wu, Yiping
Wang, Feng
Wen, Ying
Yang, Haifeng
author_sort Xu, Ting
collection PubMed
description A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management of blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated polycaprolactone@polypyrrole fibers modified indium-tin oxide (denoted as CuO/PCL@PPy/ITO) electrode has been fabricated by electrospinning combined with the electrodeposition method for non-enzymatic detection of glucose in saliva fluid. The electrospun composite fibers exhibit high sensitivity for the glucose detection. The synergistic effect between CuO and PPy together with the unique three-dimensional net structure contributes the reliable selectivity, good test repeatability, large-scale production reproducibility in massive way, the reasonable stability and a high catalytic surface area to the sensor. Quantitative detection of glucose is determined in the linear range from 2 μM to 6 mM and the lowest detection limit is 0.8 μM. The CuO/PCL@PPy/ITO electrode shows potential for the non-invasive detection of salivary glucose.
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spelling pubmed-58696242018-03-28 Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva Xu, Ting Jin, Wen Wang, Zhenzhen Cheng, Haiyan Huang, Xinhua Guo, Xiaoyu Ying, Ye Wu, Yiping Wang, Feng Wen, Ying Yang, Haifeng Nanomaterials (Basel) Article A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management of blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated polycaprolactone@polypyrrole fibers modified indium-tin oxide (denoted as CuO/PCL@PPy/ITO) electrode has been fabricated by electrospinning combined with the electrodeposition method for non-enzymatic detection of glucose in saliva fluid. The electrospun composite fibers exhibit high sensitivity for the glucose detection. The synergistic effect between CuO and PPy together with the unique three-dimensional net structure contributes the reliable selectivity, good test repeatability, large-scale production reproducibility in massive way, the reasonable stability and a high catalytic surface area to the sensor. Quantitative detection of glucose is determined in the linear range from 2 μM to 6 mM and the lowest detection limit is 0.8 μM. The CuO/PCL@PPy/ITO electrode shows potential for the non-invasive detection of salivary glucose. MDPI 2018-02-27 /pmc/articles/PMC5869624/ /pubmed/29495508 http://dx.doi.org/10.3390/nano8030133 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xu, Ting
Jin, Wen
Wang, Zhenzhen
Cheng, Haiyan
Huang, Xinhua
Guo, Xiaoyu
Ying, Ye
Wu, Yiping
Wang, Feng
Wen, Ying
Yang, Haifeng
Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title_full Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title_fullStr Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title_full_unstemmed Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title_short Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva
title_sort electrospun cuo-nanoparticles-modified polycaprolactone @polypyrrole fibers: an application to sensing glucose in saliva
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869624/
https://www.ncbi.nlm.nih.gov/pubmed/29495508
http://dx.doi.org/10.3390/nano8030133
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