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Personalised drug repositioning for Clear Cell Renal Cell Carcinoma using gene expression

Reversal of cancer gene expression is predictive of therapeutic potential and can be used to find new indications for existing drugs (drug repositioning). Gene expression reversal potential is currently calculated, in almost all studies, by pre-aggregating all tumour samples into a single group sign...

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Detalles Bibliográficos
Autores principales:	Koudijs, Karel K. M., Terwisscha van Scheltinga, Anton G. T., Böhringer, Stefan, Schimmel, Kirsten J. M., Guchelaar, Henk-Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869697/ https://www.ncbi.nlm.nih.gov/pubmed/29588458 http://dx.doi.org/10.1038/s41598-018-23195-8

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