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A hidden Markov tree model for testing multiple hypotheses corresponding to Gene Ontology gene sets
BACKGROUND: Testing predefined gene categories has become a common practice for scientists analyzing high throughput transcriptome data. A systematic way of testing gene categories leads to testing hundreds of null hypotheses that correspond to nodes in a directed acyclic graph. The relationships am...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869792/ https://www.ncbi.nlm.nih.gov/pubmed/29587646 http://dx.doi.org/10.1186/s12859-018-2106-5 |