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A hidden Markov tree model for testing multiple hypotheses corresponding to Gene Ontology gene sets

BACKGROUND: Testing predefined gene categories has become a common practice for scientists analyzing high throughput transcriptome data. A systematic way of testing gene categories leads to testing hundreds of null hypotheses that correspond to nodes in a directed acyclic graph. The relationships am...

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Detalles Bibliográficos
Autores principales: Liang, Kun, Du, Chuanlong, You, Hankun, Nettleton, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869792/
https://www.ncbi.nlm.nih.gov/pubmed/29587646
http://dx.doi.org/10.1186/s12859-018-2106-5

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