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Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho
The alarming issue of antibiotic resistance expansion requires a continuous search for new and efficient antibacterial agents. Here we describe the design of new tools to screen for target-specific inhibitors of the bacterial Rho factor directly inside eukaryotic cells. Rho factor is a global regula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869860/ https://www.ncbi.nlm.nih.gov/pubmed/29371644 http://dx.doi.org/10.1038/s41429-017-0007-x |