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Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho

The alarming issue of antibiotic resistance expansion requires a continuous search for new and efficient antibacterial agents. Here we describe the design of new tools to screen for target-specific inhibitors of the bacterial Rho factor directly inside eukaryotic cells. Rho factor is a global regula...

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Detalles Bibliográficos
Autores principales:	Moreau, Kévin, Surand, Justine, Le Dantec, Aurélia, Mosrin-Huaman, Christine, Legrand, Alain, Rahmouni, A. Rachid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869860/ https://www.ncbi.nlm.nih.gov/pubmed/29371644 http://dx.doi.org/10.1038/s41429-017-0007-x

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