Defining the Damaged DNA Mobility Paradox as Revealed by the Study of Telomeres, DSBs, Microtubules and Motors

Eukaryotic genomes are non-randomly arranged inside the nucleus. Despite this ordered spatial genome organization, damaged DNA exhibits increased random mobility within nuclear space. This increased random movement is thought to promote DNA repair by facilitating homology search, allowing targeting...

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Detalles Bibliográficos
Autor principal: Mekhail, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869915/
https://www.ncbi.nlm.nih.gov/pubmed/29616083
http://dx.doi.org/10.3389/fgene.2018.00095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869915/
https://www.ncbi.nlm.nih.gov/pubmed/29616083
http://dx.doi.org/10.3389/fgene.2018.00095

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