Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABA(A)R–TrkB interaction in minimal hepatic encephalopathy

BACKGROUND: It has been reported that D1 receptor (D(1)R) activation reduces GABA(A) receptor (GABA(A)R) current, and baicalin (BAI) displays therapeutic efficacy in diseases involving cognitive impairment. METHODS: We investigated the mechanisms by which BAI could improve DA-induced minimal hepatic...

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Detalles Bibliográficos
Autores principales: Ding, Saidan, Zhuge, Weishan, Hu, Jiangnan, Yang, Jianjing, Wang, Xuebao, Wen, Fangfang, Wang, Chengde, Zhuge, Qichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869945/
https://www.ncbi.nlm.nih.gov/pubmed/29404643
http://dx.doi.org/10.1007/s00213-018-4833-8

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