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De novo design of constrained and sequence-independent peptide scaffolds with topologically-formidable disulfide connectivities
Disulfide-rich peptides are interesting scaffolds for drug design and discovery. However, peptide scaffolds constrained by disulfide bonds, either naturally occurring or computationally designed, have been suffering from the elusive (oxidative) folding behavior complying with Anfinsen's dogma,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869988/ https://www.ncbi.nlm.nih.gov/pubmed/29629120 http://dx.doi.org/10.1039/c7sc03956e |