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The Unexpected Role of Aβ(1-42) Monomers in the Pathogenesis of Alzheimer’s Disease

Amyloid-β (Aβ) has been proposed as a biomarker and a drug target for the therapy of Alzheimer’s disease (AD). The neurotoxic entity and relevance of each conformational form of Aβ to AD pathology is still under debate; Aβ oligomers are considered the major killer form of the peptide whereas monomer...

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Detalles Bibliográficos
Autores principales:	Tamagno, Elena, Guglielmotto, Michela, Monteleone, Debora, Manassero, Giusi, Vasciaveo, Valeria, Tabaton, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870015/ https://www.ncbi.nlm.nih.gov/pubmed/29103036 http://dx.doi.org/10.3233/JAD-170581

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