Cargando…

Exercise increases circulating GDF15 in humans

OBJECTIVE: The growth differentiation factor 15 (GDF15) is a stress-sensitive circulating factor that regulates systemic energy balance. Since exercise is a transient physiological stress that has pleiotropic effects on whole-body energy metabolism, we herein explored the effect of exercise on a) ci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kleinert, Maximilian, Clemmensen, Christoffer, Sjøberg, Kim A., Carl, Christian Strini, Jeppesen, Jacob Fuglsbjerg, Wojtaszewski, Jørgen F.P., Kiens, Bente, Richter, Erik A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870087/ https://www.ncbi.nlm.nih.gov/pubmed/29398617 http://dx.doi.org/10.1016/j.molmet.2017.12.016

Ejemplares similares

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
por: Klein, Anders B., et al.
Publicado: (2021)

Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
por: Kanta, Josephine M., et al.
Publicado: (2023)

Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates
por: Lundsgaard, Anne-Marie, et al.
Publicado: (2016)

Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle–Signaling Interaction at the Level of TBC1 Domain Family Member 4
por: Pehmøller, Christian, et al.
Publicado: (2012)

ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα(2)
por: Fritzen, Andreas Mæchel, et al.
Publicado: (2020)

Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling
por: Høeg, Louise D., et al.
Publicado: (2011)

Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle
por: Sylow, Lykke, et al.
Publicado: (2013)

The Role of GDF15 as a Myomitokine
por: Johann, Kornelia, et al.
Publicado: (2021)

Enhanced Fatty Acid Oxidation and FATP4 Protein Expression after Endurance Exercise Training in Human Skeletal Muscle
por: Jeppesen, Jacob, et al.
Publicado: (2012)

Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation
por: Knudsen, Jonas R., et al.
Publicado: (2020)

LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK
por: Jeppesen, Jacob, et al.
Publicado: (2013)

Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle
por: Hingst, Janne R., et al.
Publicado: (2018)

AMPK and Insulin Action - Responses to Ageing and High Fat Diet
por: Frøsig, Christian, et al.
Publicado: (2013)

Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
por: Jall, Sigrid, et al.
Publicado: (2020)

DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
por: Zhang, Juan, et al.
Publicado: (2021)

Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training
por: Jerobin, Jayakumar, et al.
Publicado: (2021)

GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans
por: Plomgaard, Peter, et al.
Publicado: (2022)

GDF15 and Growth Control
por: Emmerson, Paul J., et al.
Publicado: (2018)

Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome
por: Melvin, A., et al.
Publicado: (2019)

GDF‐15 (Growth Differentiation Factor 15) Is Associated With Hospitalization and Mortality in Patients With a Fontan Circulation
por: Meyer, Sophie L., et al.
Publicado: (2020)

Response to Comment on: Høeg et al. Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling. Diabetes 2011;60:64–73
por: Kiens, Bente, et al.
Publicado: (2011)

GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
por: Patel, Satish, et al.
Publicado: (2019)

Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy
por: Fejzo, M, et al.
Publicado: (2023)

Effect of exercise training on skeletal muscle protein expression in relation to insulin sensitivity: Per‐protocol analysis of a randomized controlled trial (GO‐ACTIWE)
por: Bruhn, Lea, et al.
Publicado: (2021)

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
por: Kleinert, Maximilian, et al.
Publicado: (2016)

Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
por: Kleinert, Maximilian, et al.
Publicado: (2018)

Role of GDF15 in active lifestyle induced metabolic adaptations and acute exercise response in mice
por: Gil, Carla Igual, et al.
Publicado: (2019)

Altered circulating GDF-15 level predicts sex hormone imbalance in males with major depressive disorder
por: Li, Ying, et al.
Publicado: (2023)

The Importance of Fatty Acids as Nutrients during Post-Exercise Recovery
por: Lundsgaard, Anne-Marie, et al.
Publicado: (2020)

Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes
por: Sabaratnam, Rugivan, et al.
Publicado: (2018)

GDF15 promotes EMT and metastasis in colorectal cancer
por: Li, Chen, et al.
Publicado: (2015)

TGF-β contamination of purified recombinant GDF15
por: Olsen, Oddrun Elise, et al.
Publicado: (2017)

Control of glioma cell migration and invasiveness by GDF-15
por: Codó, Paula, et al.
Publicado: (2016)

GDF-15 como Biomarcador em Doenças Cardiovasculares
por: May, Bruna Miers, et al.
Publicado: (2021)

Design and Synthesis of AMPK Activators and GDF15 Inducers
por: Zhang, Meijian, et al.
Publicado: (2023)

Altered GDF15 and FGF21 Levels in Response to Strenuous Exercise: A Study in Marathon Runners
por: Campderrós, Laura, et al.
Publicado: (2020)

Circulating levels of GDF-15 and calprotectin for prediction of in-hospital mortality in COVID-19 patients: A case series
por: Luis García de Guadiana Romualdo, et al.
Publicado: (2021)

Association Between Circulating GDF‐15 and Cardio‐Renal Outcomes and Effect of Canagliflozin: Results From the CANVAS Trial
por: Sen, Taha, et al.
Publicado: (2021)

Circulating FGF21 and GDF15 as Biomarkers for Screening, Diagnosis, and Severity Assessment of Primary Mitochondrial Disorders in Children
por: Li, Yi, et al.
Publicado: (2022)

Adaptations in Mitochondrial Enzymatic Activity Occurs Independent of Genomic Dosage in Response to Aerobic Exercise Training and Deconditioning in Human Skeletal Muscle
por: Fritzen, Andreas M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_krtss5gvp9dtipicm806q9dcj4