Cargando…
A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction
OBJECTIVE: Regulation of fatty acid (FA) metabolism is central to adipocyte dysfunction during diet-induced obesity (DIO). Long-chain acyl-CoA synthetase-4 (ACSL4) has been hypothesized to modulate the metabolic fates of polyunsaturated FA (PUFA), including arachidonic acid (AA), but the in vivo act...
Autores principales: | Killion, Elizabeth A., Reeves, Andrew R., El Azzouny, Mahmoud A., Yan, Qing-Wu, Surujon, Defne, Griffin, John D., Bowman, Thomas A., Wang, Chunyan, Matthan, Nirupa R., Klett, Eric L., Kong, Dong, Newman, John W., Han, Xianlin, Lee, Mi-Jeong, Coleman, Rosalind A., Greenberg, Andrew S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870107/ https://www.ncbi.nlm.nih.gov/pubmed/29398618 http://dx.doi.org/10.1016/j.molmet.2018.01.012 |
Ejemplares similares
-
Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption
por: Bowman, Thomas A., et al.
Publicado: (2016) -
Activity of the acyl-CoA synthetase ACSL6 isoforms: role of the fatty acid Gate-domains
por: Soupene, Eric, et al.
Publicado: (2010) -
Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates
por: Lopes-Marques, Mónica, et al.
Publicado: (2013) -
Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)
por: Recuero-Checa, Maria A., et al.
Publicado: (2016) -
Overexpression of Acyl-CoA Ligase 4 (ACSL4) in Patients with Hepatocellular Carcinoma and its Prognosis
por: Sun, Xiao-Jie, et al.
Publicado: (2017)