Cargando…

Sinomenine Attenuates Chronic Intermittent Hypoxia-Induced Lung Injury by Inhibiting Inflammation and Oxidative Stress

BACKGROUND: In the present study, we aimed to investigate the effects of sinomenine (SIN) on chronic intermittent hypoxia (CIH)- induced lung injury in rats, and to explore the underlying mechanisms. MATERIAL/METHODS: To perform the investigation, a CIH rat model was established. ELISA assay was app...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaofeng, Rui, Lijun, Wang, Mei, Lian, Hairong, Cai, Liming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870109/ https://www.ncbi.nlm.nih.gov/pubmed/29549235 http://dx.doi.org/10.12659/MSM.906577

Ejemplares similares

Protective Effects of Sinomenine Against Ankylosing Spondylitis and the Underlying Molecular Mechanisms
por: Dong, Bo
Publicado: (2018)

HIPK1 Interference Attenuates Inflammation and Oxidative Stress of Acute Lung Injury via Autophagy
por: Meng, Lan, et al.
Publicado: (2019)

Adiponectin Relieves Human Adult Cardiac Myocytes Injury Induced by Intermittent Hypoxia
por: Zhang, Xiaofeng, et al.
Publicado: (2019)

Biological Network Model of Effect of Chronic Intermittent Hypoxia on Spermatogenesis in Rats
por: Wang, Jisheng, et al.
Publicado: (2020)

Toll-Like Receptor 4 (TLR-4) Pathway Promotes Pulmonary Inflammation in Chronic Intermittent Hypoxia-Induced Obstructive Sleep Apnea
por: Yang, Jiao-Jiao, et al.
Publicado: (2018)

Sinomenine Improves Embryo Survival by Regulating Th1/Th2 Balance in a Mouse Model of Recurrent Spontaneous Abortion
por: Luo, Jin, et al.
Publicado: (2021)

Effect of Intermittent Hypoxia and Rimonabant on Glucose Metabolism in Rats: Involvement of Expression of GLUT4 in Skeletal Muscle
por: Wang, Xiaoya, et al.
Publicado: (2015)

Pathogenesis of Abnormal Hepatic Lipid Metabolism Induced by Chronic Intermittent Hypoxia in Rats and the Therapeutic Effect of N-Acetylcysteine
por: Wang, Haipeng, et al.
Publicado: (2018)

Doxycycline Improves Fibrosis-Induced Abnormalities in Atrial Conduction and Vulnerability to Atrial Fibrillation in Chronic Intermittent Hypoxia Rats
por: Ma, Zuowang, et al.
Publicado: (2020)

Cell-Autonomous Autophagy Protects Against Chronic Intermittent Hypoxia Induced Sensory Nerves and Endothelial Dysfunction of the Soft Palate
por: Li, Cong, et al.
Publicado: (2020)

Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation
por: Ding, Wei, et al.
Publicado: (2015)

Barbaloin Attenuates Mucosal Damage in Experimental Models of Rat Colitis by Regulating Inflammation and the AMPK Signaling Pathway
por: Gai, Ling, et al.
Publicado: (2019)

Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy
por: Li, Guangcai, et al.
Publicado: (2017)

Sinomenine attenuates airway inflammation and remodeling in a mouse model of asthma
por: BAO, HAI-RONG, et al.
Publicado: (2016)

Biochanin A Provides Neuroprotection Against Cerebral Ischemia/Reperfusion Injury by Nrf2-Mediated Inhibition of Oxidative Stress and Inflammation Signaling Pathway in Rats
por: Guo, Minmin, et al.
Publicado: (2019)

Catalpol Attenuates IL-1β Induced Matrix Catabolism, Apoptosis and Inflammation in Rat Chondrocytes and Inhibits Cartilage Degeneration
por: Zeng, Yun-fu, et al.
Publicado: (2019)

The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress
por: Chen, Xuemei, et al.
Publicado: (2020)

Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB)
por: Han, Qianqian, et al.
Publicado: (2019)

Tilianin Post-Conditioning Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondrial Protection and Inhibition of Apoptosis
por: Wang, Yangyang, et al.
Publicado: (2017)

Hydrogen Sulfide Attenuates Hypertensive Inflammation via Regulating Connexin Expression in Spontaneously Hypertensive Rats
por: Ni, Xin, et al.
Publicado: (2018)

Chiropractic Therapy Modulated Gut Microbiota and Attenuated Allergic Airway Inflammation in an Immature Rat Model
por: Zhu, Yan, et al.
Publicado: (2020)

Dexmedetomidine Attenuates Lung Injury by Promoting Mitochondrial Fission and Oxygen Consumption
por: Zhang, Jian-Rong, et al.
Publicado: (2019)

Chemical Chaperone 4-Phenylbutyric Acid Reduces Cardiac Ischemia/Reperfusion Injury by Alleviating Endoplasmic Reticulum Stress and Oxidative Stress
por: Jian, Lian, et al.
Publicado: (2016)

Baicalein Protects Rats with Diabetic Cardiomyopathy Against Oxidative Stress and Inflammation Injury via Phosphatidylinositol 3-Kinase (PI3K)/AKT Pathway
por: Ma, Lin, et al.
Publicado: (2018)

Interleukin-37 Attenuates Lipopolysaccharide (LPS)-Induced Neonatal Acute Respiratory Distress Syndrome in Young Mice via Inhibition of Inflammation and Cell Apoptosis
por: Li, Bo, et al.
Publicado: (2020)

Curcumin Attenuates Inflammation in a Severe Acute Pancreatitis Animal Model by Regulating TRAF1/ASK1 Signaling
por: Yu, Shuo, et al.
Publicado: (2018)

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Cyclosporine-A via Suppression of Mitochondrial DNA
por: Xiao, Zhenghua, et al.
Publicado: (2018)

Controlled Decompression Attenuates Brain Injury in a Novel Rabbit Model of Acute Intracranial Hypertension
por: Guan, Haoxiang, et al.
Publicado: (2019)

Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats
por: Tian, Sheng-Lan, et al.
Publicado: (2018)

Mercaptoethanol Protects the Aorta from Dissection by Inhibiting Oxidative Stress, Inflammation, and Extracellular Matrix Degeneration in a Mouse Model
por: Zhang, Lei, et al.
Publicado: (2018)

Maresin-1 Inhibits Oxidative Stress and Inflammation and Promotes Apoptosis in a Mouse Model of Caerulein-Induced Acute Pancreatitis
por: Lv, Chengjie, et al.
Publicado: (2019)

Blockade of Extracellular High-Mobility Group Box 1 Attenuates Systemic Inflammation and Coagulation Abnormalities in Rats with Acute Traumatic Coagulopathy
por: Xu, Lin, et al.
Publicado: (2016)

Lutein Suppresses Oxidative Stress and Inflammation by Nrf2 Activation in an Osteoporosis Rat Model
por: Li, Hongtao, et al.
Publicado: (2018)

Calcitonin Gene-Related Peptide Attenuates LPS-Induced Acute Kidney Injury by Regulating Sirt1
por: Liu, Pingli, et al.
Publicado: (2020)

Atorvastatin Induces Hepatotoxicity in Diabetic Rats via Oxidative Stress, Inflammation, and Anti-Apoptotic Pathway
por: Zeng, Hanqing, et al.
Publicado: (2019)

Inflammation induced by increased frequency of intermittent hypoxia is attenuated by tempol administration
por: Zhang, J., et al.
Publicado: (2015)

Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation
por: Xia, Boyu, et al.
Publicado: (2022)

Epigallocatechin Gallate Attenuates Hip Fracture-Induced Acute Lung Injury by Limiting Mitochondrial DNA (mtDNA) Release
por: Zhao, Xiao-dan, et al.
Publicado: (2017)

Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling
por: Ji, Xingli, et al.
Publicado: (2018)

Intermittent Fasting Improves Lipid Metabolism Through Changes in Gut Microbiota in Diet-Induced Obese Mice
por: Deng, Ya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f5q889km1lulppkjr445l35h5c