Cargando…
Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins
A practical three-step protocol for the assembly of triazolobenzodiazepine-fused diketopiperazines and hydantoins has been developed. The synthesis of these tetracyclic ring systems was initiated by an Ugi reaction, which brought together all necessary functionalities for further transformations. Th...
Autores principales: | Vroemans, Robby, Bamba, Fante, Winters, Jonas, Thomas, Joice, Jacobs, Jeroen, Van Meervelt, Luc, John, Jubi, Dehaen, Wim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870159/ https://www.ncbi.nlm.nih.gov/pubmed/29623124 http://dx.doi.org/10.3762/bjoc.14.49 |
Ejemplares similares
-
Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach
por: P, Rahul, et al.
Publicado: (2022) -
5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
por: Vroemans, Robby, et al.
Publicado: (2020) -
Assembly of fully substituted triazolochromenes via a novel multicomponent reaction or mechanochemical synthesis
por: Vroemans, Robby, et al.
Publicado: (2018) -
One-Pot Ugi/Aza-Michael Synthesis of Highly Substituted 2,5-Diketopiperazines with Anti-Proliferative Properties
por: Hartung, Andreas, et al.
Publicado: (2012) -
An intramolecular hydrogen bond-promoted “green” Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity
por: Li, Jie, et al.
Publicado: (2022)