Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains

BACKGROUND: Within the polymicrobial dental plaque biofilm, bacteria kill competitors by excreting mixtures of bacteriocins, resulting in improved fitness and survival. Inhibiting their bacteriocin synthesis might therefore be a useful strategy to eliminate specific pathogens. We used Streptococcus...

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Detalles Bibliográficos
Autores principales: Premnath, Priyanka, Reck, Michael, Wittstein, Kathrin, Stadler, Marc, Wagner-Döbler, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870221/
https://www.ncbi.nlm.nih.gov/pubmed/29580208
http://dx.doi.org/10.1186/s12866-018-1170-3