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Pioglitazone is effective for multiple phenotyepes of the Zucker fa/fa rat with polycystc ovary morphology and insulin resistance
BACKGROUND: Hyperandrogenism and insulin resistance may be related to the etiology of PCOS. Zucker fa/fa rats with polycystic ovary are obese, have insulin resistance without diabetes mellitus or hyperandrogenism and can be utilized as PCOS model rats without effects of hyperandrogenemia. PCOS patie...
Autores principales: | Morishita, Miyuki, Endo, Toshiaki, Baba, Tsuyoshi, Kuno, Yoshika, Ikeda, Keiko, Kiya, Tamotsu, Honnma, Hiroyuki, Saito, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870225/ https://www.ncbi.nlm.nih.gov/pubmed/29580285 http://dx.doi.org/10.1186/s13048-018-0395-y |
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