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Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo
OBJECTIVE: We had previously reported a mouse line carrying the Atypical female courtship (HoxD(Afc)) allele, where an ectopic accumulation of Hoxd10 transcripts was observed in a sparse population of cells in the adult isocortex, as a result of a partial deletion of the HoxD gene cluster. Female mi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870235/ https://www.ncbi.nlm.nih.gov/pubmed/29580290 http://dx.doi.org/10.1186/s13104-018-3307-8 |