In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes porcine reproductive and respiratory syndrome (PRRS), which is currently insufficiently controlled. From a previous small-scale screen we identified an effective DNA-based short antisense oligonucleotide (AS-ON) targeting...

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Detalles Bibliográficos
Autores principales: Zhu, Lingyun, Bi, Junlong, Zheng, Longlong, Zhao, Qian, Shu, Xianghua, Guo, Gang, Liu, Jia, Yang, Guishu, Liu, Jianping, Yin, Gefen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870238/
https://www.ncbi.nlm.nih.gov/pubmed/29580234
http://dx.doi.org/10.1186/s12917-018-1432-1

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