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A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97

BACKGROUND: Prostate cancer (PCa) is a major cause of morbidity and mortality in men worldwide. MicroRNAs are globally downregulated in PCa, especially in poorly differentiated tumors. Nonetheless, the underlying mechanisms are still elusive. Herein, using combined analysis of microRNAs expression a...

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Detalles Bibliográficos
Autores principales: Ramalho-Carvalho, João, Gonçalves, Céline S., Graça, Inês, Bidarra, David, Pereira-Silva, Eva, Salta, Sofia, Godinho, Maria Inês, Gomez, Antonio, Esteller, Manel, Costa, Bruno M., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870254/
https://www.ncbi.nlm.nih.gov/pubmed/29599847
http://dx.doi.org/10.1186/s13148-018-0475-2