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Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography

PURPOSE: To determine the intra-session and inter-session reproducibility of corneal, macular and retinal nerve fiber layer thickness (RNFL) measurements with the iVue-100 optical coherence tomography in normal eyes. METHODS: These parameters were measured in the right eyes of 50 healthy participant...

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Autor principal: Mashige, Khathutshelo P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870293/
https://www.ncbi.nlm.nih.gov/pubmed/29937896
http://dx.doi.org/10.4314/ahs.v17i4.33
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author Mashige, Khathutshelo P
author_facet Mashige, Khathutshelo P
author_sort Mashige, Khathutshelo P
collection PubMed
description PURPOSE: To determine the intra-session and inter-session reproducibility of corneal, macular and retinal nerve fiber layer thickness (RNFL) measurements with the iVue-100 optical coherence tomography in normal eyes. METHODS: These parameters were measured in the right eyes of 50 healthy participants with normal vision. Six scans each for corneal thickness, macular and optic nerve head were taken on one day (intra-session), followed by similar repeated measures on five separate days (inter-session). Reproducibility was computed using intra-class correlation coefficient (ICC), coefficient of variation (COV), and test-retest variability (TRV). RESULTS: For intra-session reproducibility, the ICC, COV and TRV values for mean corneal thickness were 0.924, 2.82%, and 3.06 µm respectively. For the mean macular thickness, they were 0.978, 4.64% and 4.51 µm respectively, while for mean RNFL thickness they were 0.946, 3.19%, and 5.66 µm respectively. Inter-session values for mean corneal thickness were 0.926, 2.65% and 3.48 µm, and 0.916, 2.24% and 2.03 µm for mean macular thickness. For mean RNFL thickness, they were 0.962, 2.21%, and 4.72 µm respectively. CONCLUSION: There was good reproducibility of all measured parameters. However, mean RNFL thickness measurements were the most reproducible, suggesting that this may be the best parameter to use to determine measured changes over time.
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spelling pubmed-58702932018-06-22 Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography Mashige, Khathutshelo P Afr Health Sci Articles PURPOSE: To determine the intra-session and inter-session reproducibility of corneal, macular and retinal nerve fiber layer thickness (RNFL) measurements with the iVue-100 optical coherence tomography in normal eyes. METHODS: These parameters were measured in the right eyes of 50 healthy participants with normal vision. Six scans each for corneal thickness, macular and optic nerve head were taken on one day (intra-session), followed by similar repeated measures on five separate days (inter-session). Reproducibility was computed using intra-class correlation coefficient (ICC), coefficient of variation (COV), and test-retest variability (TRV). RESULTS: For intra-session reproducibility, the ICC, COV and TRV values for mean corneal thickness were 0.924, 2.82%, and 3.06 µm respectively. For the mean macular thickness, they were 0.978, 4.64% and 4.51 µm respectively, while for mean RNFL thickness they were 0.946, 3.19%, and 5.66 µm respectively. Inter-session values for mean corneal thickness were 0.926, 2.65% and 3.48 µm, and 0.916, 2.24% and 2.03 µm for mean macular thickness. For mean RNFL thickness, they were 0.962, 2.21%, and 4.72 µm respectively. CONCLUSION: There was good reproducibility of all measured parameters. However, mean RNFL thickness measurements were the most reproducible, suggesting that this may be the best parameter to use to determine measured changes over time. Makerere Medical School 2017-12 /pmc/articles/PMC5870293/ /pubmed/29937896 http://dx.doi.org/10.4314/ahs.v17i4.33 Text en © 2017 Mashige KP. Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Mashige, Khathutshelo P
Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title_full Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title_fullStr Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title_full_unstemmed Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title_short Reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the iVue-100 optical coherence tomography
title_sort reproducibility of corneal, macular and retinal nerve fiber layer thickness measurements using the ivue-100 optical coherence tomography
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870293/
https://www.ncbi.nlm.nih.gov/pubmed/29937896
http://dx.doi.org/10.4314/ahs.v17i4.33
work_keys_str_mv AT mashigekhathutshelop reproducibilityofcornealmacularandretinalnervefiberlayerthicknessmeasurementsusingtheivue100opticalcoherencetomography