Patient-derived lymphoblastoid cell lines harboring mitochondrial DNA mutations as tool for small molecule drug discovery

OBJECTIVE: Mitochondrial diseases are a group of devastating disorders for which there is no transformative cure. The majority of therapies for mitochondrial disease—approved, previously tested, or currently in development—are small molecules. The implementation of better cell-based models of mitoch...

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Detalles Bibliográficos
Autores principales: Chin, Randall Marcelo, Panavas, Tadas, Brown, Jeffrey M., Johnson, Krista K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870301/
https://www.ncbi.nlm.nih.gov/pubmed/29587845
http://dx.doi.org/10.1186/s13104-018-3297-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870301/
https://www.ncbi.nlm.nih.gov/pubmed/29587845
http://dx.doi.org/10.1186/s13104-018-3297-6

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