Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

BACKGROUND: Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and others find that YAP is up-regulated in pancreatic ductal adenocarcinoma (PDAC) and associated with worse prognosis of patients. Acti...

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Detalles Bibliográficos
Autores principales: Jiang, Zhengdong, Zhou, Cancan, Cheng, Liang, Yan, Bin, Chen, Ke, Chen, Xin, Zong, Liang, Lei, Jianjun, Duan, Wanxing, Xu, Qinhong, Li, Xuqi, Wang, Zheng, Ma, Qingyong, Ma, Jiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870346/
https://www.ncbi.nlm.nih.gov/pubmed/29587800
http://dx.doi.org/10.1186/s13046-018-0740-4

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