Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

BACKGROUND: TREM2 is an innate immune receptor specifically expressed in microglia. Coding variations in TREM2 have been reported to increase the risk for Alzheimer’s disease (AD) and other neurodegenerative diseases. While multiple studies support a role for TREM2 in microglial recruitment to amylo...

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Detalles Bibliográficos
Autores principales: Zhong, Li, Wang, Zongqi, Wang, Daxin, Wang, Zhe, Martens, Yuka A., Wu, Linbei, Xu, Ying, Wang, Kai, Li, Jianguo, Huang, Ruizhi, Can, Dan, Xu, Huaxi, Bu, Guojun, Chen, Xiao-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://www.ncbi.nlm.nih.gov/pubmed/29587871
http://dx.doi.org/10.1186/s13024-018-0247-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870375/
https://www.ncbi.nlm.nih.gov/pubmed/29587871
http://dx.doi.org/10.1186/s13024-018-0247-7

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