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Dual vicinal functionalisation of heterocycles via an interrupted Pummerer coupling/[3,3]-sigmatropic rearrangement cascade
A dual vicinal functionalisation cascade involving the union of heterocycles and allyl sulfoxides is described. In particular, the approach provides efficient one-step access to biologically relevant and synthetically important C3 thio, C2 carbo substituted indoles. The reaction operates under mild,...
Autores principales: | Šiaučiulis, Mindaugas, Sapmaz, Selma, Pulis, Alexander P., Procter, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870476/ https://www.ncbi.nlm.nih.gov/pubmed/29629145 http://dx.doi.org/10.1039/c7sc04723a |
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