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Pulling the genome in opposite directions to dissect gene networks

Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies.

Detalles Bibliográficos
Autores principales: Gersbach, Charles A., Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870483/
https://www.ncbi.nlm.nih.gov/pubmed/29580291
http://dx.doi.org/10.1186/s13059-018-1425-1
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author Gersbach, Charles A.
Barrangou, Rodolphe
author_facet Gersbach, Charles A.
Barrangou, Rodolphe
author_sort Gersbach, Charles A.
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description Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies.
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spelling pubmed-58704832018-03-29 Pulling the genome in opposite directions to dissect gene networks Gersbach, Charles A. Barrangou, Rodolphe Genome Biol Research Highlight Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies. BioMed Central 2018-03-26 /pmc/articles/PMC5870483/ /pubmed/29580291 http://dx.doi.org/10.1186/s13059-018-1425-1 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Gersbach, Charles A.
Barrangou, Rodolphe
Pulling the genome in opposite directions to dissect gene networks
title Pulling the genome in opposite directions to dissect gene networks
title_full Pulling the genome in opposite directions to dissect gene networks
title_fullStr Pulling the genome in opposite directions to dissect gene networks
title_full_unstemmed Pulling the genome in opposite directions to dissect gene networks
title_short Pulling the genome in opposite directions to dissect gene networks
title_sort pulling the genome in opposite directions to dissect gene networks
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870483/
https://www.ncbi.nlm.nih.gov/pubmed/29580291
http://dx.doi.org/10.1186/s13059-018-1425-1
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