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Pulling the genome in opposite directions to dissect gene networks
Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870483/ https://www.ncbi.nlm.nih.gov/pubmed/29580291 http://dx.doi.org/10.1186/s13059-018-1425-1 |
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author | Gersbach, Charles A. Barrangou, Rodolphe |
author_facet | Gersbach, Charles A. Barrangou, Rodolphe |
author_sort | Gersbach, Charles A. |
collection | PubMed |
description | Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies. |
format | Online Article Text |
id | pubmed-5870483 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-58704832018-03-29 Pulling the genome in opposite directions to dissect gene networks Gersbach, Charles A. Barrangou, Rodolphe Genome Biol Research Highlight Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies. BioMed Central 2018-03-26 /pmc/articles/PMC5870483/ /pubmed/29580291 http://dx.doi.org/10.1186/s13059-018-1425-1 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Highlight Gersbach, Charles A. Barrangou, Rodolphe Pulling the genome in opposite directions to dissect gene networks |
title | Pulling the genome in opposite directions to dissect gene networks |
title_full | Pulling the genome in opposite directions to dissect gene networks |
title_fullStr | Pulling the genome in opposite directions to dissect gene networks |
title_full_unstemmed | Pulling the genome in opposite directions to dissect gene networks |
title_short | Pulling the genome in opposite directions to dissect gene networks |
title_sort | pulling the genome in opposite directions to dissect gene networks |
topic | Research Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870483/ https://www.ncbi.nlm.nih.gov/pubmed/29580291 http://dx.doi.org/10.1186/s13059-018-1425-1 |
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