Atrophy of primary lymphoid organs induced by Marek’s disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia

Marek’s disease is a multi-faceted highly contagious disease affecting chickens caused by the Marek’s disease alphaherpesvirus (MDV). MDV early infection induces a transient immunosuppression, which is associated with thymus and bursa of Fabricius atrophy. Little is known about the cellular processe...

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Autores principales: Berthault, Camille, Larcher, Thibaut, Härtle, Sonja, Vautherot, Jean-François, Trapp-Fragnet, Laetitia, Denesvre, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870490/
https://www.ncbi.nlm.nih.gov/pubmed/29587836
http://dx.doi.org/10.1186/s13567-018-0526-x

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