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Arsenic trioxide induces apoptosis and the formation of reactive oxygen species in rat glioma cells

BACKGROUND: Arsenic trioxide (As(2)O(3)) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As(2)O(3) has an antitumor effect on glioma and explored the underlying mechanism. RESULTS: M...

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Detalles Bibliográficos
Autores principales:	Sun, Yuanyuan, Wang, Chen, Wang, Ligang, Dai, Zhibo, Yang, Kongbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870496/ https://www.ncbi.nlm.nih.gov/pubmed/29610575 http://dx.doi.org/10.1186/s11658-018-0074-4

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