Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway

BACKGROUND: Tumor microenvironments (TMEs) activate various axes/pathways, predominantly inflammatory and hypoxic responses, impact tumorigenesis, metastasis and therapeutic resistance significantly. Although molecular pathways of individual TME are extensively studied, evidence showing interaction...

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Detalles Bibliográficos
Autores principales: Yeh, Yen-Hsiu, Hsiao, Ho-Fu, Yeh, Yen-Cheng, Chen, Tien-Wen, Li, Tsai-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870508/
https://www.ncbi.nlm.nih.gov/pubmed/29587825
http://dx.doi.org/10.1186/s13046-018-0730-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870508/
https://www.ncbi.nlm.nih.gov/pubmed/29587825
http://dx.doi.org/10.1186/s13046-018-0730-6

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