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Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway

BACKGROUND: Tumor microenvironments (TMEs) activate various axes/pathways, predominantly inflammatory and hypoxic responses, impact tumorigenesis, metastasis and therapeutic resistance significantly. Although molecular pathways of individual TME are extensively studied, evidence showing interaction...

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Detalles Bibliográficos
Autores principales:	Yeh, Yen-Hsiu, Hsiao, Ho-Fu, Yeh, Yen-Cheng, Chen, Tien-Wen, Li, Tsai-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870508/ https://www.ncbi.nlm.nih.gov/pubmed/29587825 http://dx.doi.org/10.1186/s13046-018-0730-6

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