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Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008
BACKGROUND: Drug resistance of B-cell precursor acute lymphoblastic leukemia (BP-ALL) cells is conferred by both intrinsic and extrinsic factors, which could be targeted to promote chemo-sensitization. Our previous studies showed that Galectin-3, a lectin that clusters galactose-modified glycoprotei...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870532/ https://www.ncbi.nlm.nih.gov/pubmed/29580262 http://dx.doi.org/10.1186/s13046-018-0721-7 |