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karyoploteR: an R/Bioconductor package to plot customizable genomes displaying arbitrary data

MOTIVATION: Data visualization is a crucial tool for data exploration, analysis and interpretation. For the visualization of genomic data there lacks a tool to create customizable non-circular plots of whole genomes from any species. RESULTS: We have developed karyoploteR, an R/Bioconductor package...

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Detalles Bibliográficos
Autores principales: Gel, Bernat, Serra, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870550/
https://www.ncbi.nlm.nih.gov/pubmed/28575171
http://dx.doi.org/10.1093/bioinformatics/btx346
Descripción
Sumario:MOTIVATION: Data visualization is a crucial tool for data exploration, analysis and interpretation. For the visualization of genomic data there lacks a tool to create customizable non-circular plots of whole genomes from any species. RESULTS: We have developed karyoploteR, an R/Bioconductor package to create linear chromosomal representations of any genome with genomic annotations and experimental data plotted along them. Plot creation process is inspired in R base graphics, with a main function creating karyoplots with no data and multiple additional functions, including custom functions written by the end-user, adding data and other graphical elements. This approach allows the creation of highly customizable plots from arbitrary data with complete freedom on data positioning and representation. AVAILABILITY AND IMPLEMENTATION: karyoploteR is released under Artistic-2.0 License. Source code and documentation are freely available through Bioconductor (http://www.bioconductor.org/packages/karyoploteR) and at the examples and tutorial page at https://bernatgel.github.io/karyoploter_tutorial.